Imikhiqizo
I-Retinoic Acid
Ifomula Yesakhiwo
Ukubukeka:Impushana e-orange ekhanyayo noma ephuzi
Ukuminyana:1.0597 (isilinganiso esinzima)
Iphoyinti lokuncibilika:180-181°C (okhanyayo)
Iphuzu elibilayo:381.66°C (isilinganiso esinzima)
I-Refractivity:1.4800 (isilinganiso)
Idatha Yezokuphepha
jikelele
Isicelo
I-Retinoic acid (i-tretinoin) iphuma ku-vitamin A.Ibonise amandla okushintsha ukwakheka kwe-collagen, ukwandisa amazinga e-dermal hyaluronic acid, futhi ikhuthaze ukukhula kwe-fibroblast kanye ne-matrix engaphandle kweselula.Isetshenziselwa ukuphazamiseka kwe-keratinization kanye nokwelapha izinduna.
I-Vitamin A, enefomula yamangqamuzana i-C20H28O2, ingumkhiqizo ophakathi we-metabolic kavithamini A emzimbeni, ikakhulukazi ethinta ukukhula kwamathambo futhi ikhuthaze imiphumela ye-metabolic yokwanda kwamangqamuzana e-epithelial, ukuhlukaniswa kanye ne-keratinolysis.Isetshenziselwa ukwelapha i-acne vulgaris, i-psoriasis, ichthyosis, i-lichen planus, i-furunculosis ebomvu yezinwele, i-follicular keratosis, i-squamous cell carcinoma ne-melanoma.
Isigaba: I-Anti-skin keratinisation abnormalities, ama-cell enducing differentiation agents
Izimo zokugcina: ukukhanya-ukukhanya futhi kuvalwe uphawu
I-Retinoic acid ayinawo umthelela emsebenzini we-tyrosinase kanye nokwakheka kwe-melanin kwama-melanocyte abantu ajwayelekile.Lapho isikhumba siguga ngokomzimba noma sonakaliswa izidakamizwa, imisebe ye-UV noma ukuhlukumezeka, i-retinoic acid ilungisa noma ivimbele ukungahambi kahle ekubunjweni kwamakhemikhali ezinto eziphilayo kanye nesakhiwo se-morphological ye-dermal connective tissue ebangelwa izici eziyingozi.I-Retinoic acid ayinawo umthelela ekuhlanganiseni kwe-collagen yesikhumba evamile.Ngaphezu kwalokho, i-retinoic acid inomsebenzi ovimbelayo ku-leukocyte chemotaxis, ngaleyo ndlela isebenza njenge-ejenti elwa nokuvuvukala.I-Retinoic acid ayinawo umthelela oqondile kuzindlala ze-sebaceous kanye nokukhiqizwa kwazo.
