Imikhiqizo
I-L-threonine
Incazelo
a.Isetshenziswa kakhulu njengesengezo sokudla okunomsoco.Ukushisa kwe-Co nge-glucose kulula ukukhiqiza ukunambitheka okushile kanye noshokoledi, okungathuthukisa ukunambitheka.Ingasetshenziswa futhi ocwaningweni lwe-biochemical.
b.I-Threonine iyi-amino acid ebalulekile njengesivikeli sezakhi zokudla.I-Threonine ivame ukungezwa ekudleni kwamantshontsho engulube nezinkukhu.Iwumkhawulo wesibili we-amino acid wokuphakelwa kwezingulube kanye nomkhawulo wesithathu wama-amino acid wokuphakelwa kwezinkukhu.Yengezwa ekudleni ikakhulukazi okuhlanganiswe ukolweni, ibhali nezinye izinhlamvu.
c.Isengezo sokudla okunomsoco, futhi sisetshenziselwa ukulungisa ukumnika kwe-amino acid kanye nokulungiswa okuphelele kwe-amino acid.
d.Isetshenziselwa ukwelashwa kwe-peptic ulcer.Ingakwazi futhi ukwelapha i-anemia, i-angina pectoris, i-arteritis, ukungasebenzi kahle kwenhliziyo nezinye izifo zenhliziyo.
e.I-Threonine (L-threonine) yahlukaniswa futhi yahlonzwa ku-fibrin hydrolyzate yi-WC rose ngo-1935. Kuye kwafakazelwa ukuthi iwukugcina i-amino acid ebalulekile etholakele.Kuyinto yesibili noma yesithathu ekhawulela i-amino acid yemfuyo nezinkukhu.Idlala indima ebaluleke kakhulu yokuphila ezilwaneni.Okufana nokukhuthaza ukukhula kanye nokwenza ngcono umsebenzi wokuzivikela komzimba;Linganisa ama-amino acid ekudleni ukuze wenze isilinganiso sama-amino acid sisondele kuphrotheni efanelekile, ukuze kwehliswe izidingo zemfuyo nezinkukhu zokuqukethwe kwamaprotheni ekudleni.Ukuntuleka kwe-threonine kungaholela ekwehleni kokudla, ukuvimbela ukukhula, ukunciphisa ukusetshenziswa kokudla, ukuvimbela umsebenzi wokuzivikela komzimba kanye nezinye izimpawu.Eminyakeni yamuva nje, i-lysine ne-methionine synthetics isetshenziswe kabanzi ekuphakeleni.I-Threonine kancane kancane isibe yisici esikhawulelayo esithinta ukusebenza kokukhiqizwa kwezilwane.Ucwaningo olwengeziwe nge-threonine luzosiza ekuqondiseni ngempumelelo imfuyo kanye nokukhiqizwa kwezinkukhu.
f.I-Threonine (L-threonine) iyi-amino acid izilwane ezingakwazi ukuyihlanganisa kodwa ziyidinga.Ingasetshenziselwa ukulinganisa ngokunembile ukwakheka kwe-amino acid yokudla, ukuhlangabezana nezidingo zokukhula nokugcinwa kwezilwane, ukuthuthukisa ukuzuza kwesisindo kanye nezinga lenyama engenamafutha, nokunciphisa isilinganiso senyama yokudla;Ingathuthukisa inani lokudla okunomsoco wezinto eziphakelayo ezinokugayeka kancane kwe-amino acid futhi ithuthukise ukusebenza kokukhiqizwa kokuphakelayo okunamandla aphansi;Inganciphisa izinga leprotheyini engahluziwe ekudleni, ithuthukise izinga lokusebenzisa i-nitrogen yokudla futhi yehlise izindleko zokudla;Ingasetshenziselwa ukufuya izingulube, izinkukhu, amadada kanye nemikhiqizo yasemanzini yezinga eliphezulu.I-L-threonine iyisengezo sokuphakelayo esikhiqizwa ukuvutshelwa okujulile koketshezi kanye nokucwengwa ngesitashi sombila nezinye izinto ezingavuthiwe ngokusekelwe kumgomo we-bioengineering.Ingakwazi ukulungisa ibhalansi ye-amino acid ekudleni, ikhuthaze ukukhula, ithuthukise ikhwalithi yenyama, ithuthukise inani lokudla okudliwayo kwempahla eluhlaza nge-digestibility ephansi ye-amino acid, futhi ikhiqize ukudla okuphansi kwamaprotheni, okusiza ukulondoloza imithombo yamaprotheni, ukunciphisa izindleko zokudla. izinto zokusetshenziswa, zinciphisa okuqukethwe kwe-nitrogen emfuyweni nasezinkukhuni nasemazingeni omchamo, kanye nokugcwala kwe-ammonia kanye nezinga lokukhululwa ezindlini zemfuyo nezinkukhu.Isetshenziswa kakhulu ukwengeza ukudla kwezingulube, ukudla kwezingulube ezizalanisayo, ukudla kwenyamazane, ukudla kwezimfanzi kanye nokudla kwama-eel.
g.I-Threonine (L-threonine) iyona kuphela i-amino acid engadluli ku-deamination kanye ne-transamination ku-catabolism yomzimba, kodwa iguqulwa ngokuqondile ibe ezinye izinto ngokusebenzisa i-catalysis ye-threonine dehydratase, i-threonine dehydrogenase ne-threonine aldolase.Isibonelo, i-threonine ingashintshwa ibe yi-butyryl coenzyme A, i-succinyl coenzyme A, i-serine, i-glycine, njll. Ngaphezu kwalokho, i-threonine ngokweqile ingandisa i-lysine- α- Umsebenzi we-ketoglucose reductase.Ukwengeza inani elifanele le-threonine ekudleni kungaqeda ukwehla kwesisindo somzimba esibangelwa i-lysine eyeqile, kanye nokuncipha kwe-protein/deoxyribonucleic acid (DNA) kanye ne-RNA/dna ratio esibindini nasezicubu zemisipha.Ukwengezwa kwe-threonine nakho kunganciphisa ukuvimbela ukukhula okubangelwa i-tryptophan noma i-methionine eyeqile.Kubikwa ukuthi ukumuncwa okunengi kwe-threonine ezinkukhwini kutholakala ku-duodenum, isivuno kanye lesisu se-glaular.Ngemva kokumuncwa, i-threonine iguqulwa ngokushesha ibe amaprotheni esibindi futhi ifakwe emzimbeni.
Ulwazi Lomkhiqizo
Inombolo yeCas: 72-19-5
Ubumsulwa:≥98.5%
Ifomula: C4H9NO3
Ifomula Wt.Igama: 119.1192
Igama Lekhemikhali: L-hydroxybutyric acid;i-α- Amino group- β- Hydroxybutyric acid;2s, 3R) - 2-amino-3-hydroxybutyric acid;I-Threonine;H-Thr-OH
Igama le-IUPAC : L-hydroxybutyric acid;i-α- Amino group- β- Hydroxybutyric acid;2s, 3R) - 2-amino-3-hydroxybutyric acid;I-Threonine;H-Thr-OH
Iphuzu Elincibilikayo :256(dec.)(lit.)
Ukunyibilika: Incibilika emanzini (200g/l, 25 ℃), ayincibiliki ku-methanol, ethanol, ether ne-chloroform.
Ukubukeka: Ikristalu emhlophe noma i-crystalline powder, equkethe 1/2 amanzi ekristalu.Ayinaphunga, imnandi kancane.
Ukuthumela kanye Nesitoreji
Isikhathi Sokugcina: Iphakheji elivaliwe ebhodleleni lengilazi yomlomo obanzi onsundu.Gcina endaweni epholile neyomile kude nokukhanya.
Isikhathi Somkhumbi: Okuvaliwe, okupholile futhi okuvuzayo.
Izithenjwa
1. I-Xuqingyang, i-fengzhibin, i-sunyuhua, njll. Umphumela we-oxygen encibilikisiwe ekuvutshelweni kwe-L-threonine.CNKI;Wanfang, 2007
2. I-Fengzhibin, i-wangdongyang, i-xuqingyang, njll. Umphumela womthombo we-nitrogen ekuvubeleni kwe-L-threonine.I-Chinese Journal of Bioengineering, 2006
