Imikhiqizo
I-Folic Acid
Ifomula Yesakhiwo
Okomzimba
Ukubukeka:Ophuzi Kuya Ku-Orange Crystalline Powder
Ukuminyana: 1.4704 (Isilinganiso esinzima)
Ukuncibilika:250 °c
Indawo yokubilisa:552.35°c (Isilinganiso esinzima)
I-Refractivity: 1.6800 (isilinganiso)
Ukuzungezisa Okuthile :20 º (c=1, 0.1n Naoh)
Isimo Sesitoreji:2-8°c
Ukuncibilika :Amanzi abilayo: I-Soluble1%
I-Acidity Factor(pka):pka 2.5 (ayiqinisekile)
Iphunga:Akunaphunga
Ukunyibilika Emanzini:1.6 Mg/l (25 ºc)
Idatha Yezokuphepha
Isigaba esiyingozi:Akuzona izimpahla eziyingozi
Inombolo yokuthutha impahla eyingozi:
Isigaba sokupakisha:
Isicelo
Isigaba esiyingozi:Akuzona izimpahla eziyingozi
Inombolo yokuthutha impahla eyingozi:
Isigaba sokupakisha:
I-folic acid ivithamini encibilika emanzini enefomula yamangqamuzana ethi C19H19N7O6, ebizwa kanjalo ngoba igcwele amaqabunga aluhlaza, aziwa nangokuthi i-pteroylglutamic acid.Ikhona ngezindlela eziningana emvelweni futhi inhlanganisela yomzali wayo iyinhlanganisela yezingxenye ezi-3: i-pteridine, i-p-aminobenzoic acid ne-glutamic acid.
I-Folic acid iqukethe iqembu elilodwa noma amaningi e-glutamyl, futhi izinhlobo ezivame kakhulu ze-folic acid zingamafomu e-polyglutamic acid.Ifomu elisebenzayo le-folic acid yi-tetrahydrofolate.I-Folic acid iyikristalu ephuzi futhi incibilika kancane emanzini, kodwa usawoti wayo we-sodium uncibilika kakhulu emanzini.Ayincibiliki ku-ethanol.Ishabalaliswa kalula ezixazululweni ezine-asidi futhi futhi ayizinzi ekushiseni, ilahleka kalula uma kuqhathaniswa nezinga lokushisa legumbi, futhi yonakala kakhulu lapho ichayeka ekukhanyeni.
I-folic acid imuncwa emzimbeni ngokusebenza nangokuzihambela ngokusakazwa, ikakhulukazi engxenyeni engenhla yamathumbu amancane.Izinga lokumuncwa kwe-folic acid encishisiwe liphakeme, lapho i-glutamyl iyancipha izinga lokumunca, futhi ukumuncwa kusiza i-glucose ne-vitamin C. Ngemva kokumuncwa, i-folic acid igcinwa odongeni lwamathumbu, isibindi, umnkantsha nezinye izicubu, futhi iyancipha ibe yi-physiologically active tetrahydrofolate (THFA noma i-FH4) nge-enzyme i-NADPH, ehilelekile ekuhlanganiseni kwama-purines nama-pyrimidines.Ngakho-ke i-folic acid idlala indima ebalulekile ekuhlanganiseni amaprotheni kanye nokuhlukana kwamangqamuzana nokukhula, futhi ikhuthaza ukwakheka kwamangqamuzana egazi abomvu avamile.Ukuntuleka kwe-folic acid kungaholela ekwehleni kokukhiqizwa kwe-hemoglobin emangqamuzaneni abomvu egazi kanye nokukhubazeka kokuvuthwa kwamangqamuzana, okuholela ku-anemia ye-megaloblastic.
