Imikhiqizo
I-Adenine
Ifomula Yesakhiwo
Okomzimba
Ukubukeka: I-crystalline emhlophe noma i-off-white crystalline powder
Ukuminyana: 1.6 g/cm³
Iphoyinti elincibilikayo: 360-365℃(>360℃(lit.))
Iphuzu elibilayo.
I-Refractivity.
Iphoyinti elikhanyayo: 220 ℃
Idatha Yezokuphepha
Isigaba esiyingozi.
Inombolo Yezokuthutha Izimpahla Eziyingozi.
Isigaba sokupakisha.
Isicelo
I-purine nucleobase kanye nengxenye ye-DNA.Kusabalele kuzo zonke izicubu zezilwane nezitshalo kuhlanganiswe ne-niacinamide, i-d-ribose, nama-phosphoric acid;ingxenye yama-nucleic acid nama-coenzymes, njenge-codehydrase I no-II, i-adenylic acid, i-coa laninedehydrase.Isetshenziselwa ukuzimisela kwe-microbial ye-niacin;ocwaningweni ngofuzo, izifo zegciwane, nomdlavuza.ukufakwa kwe-enteric kanye ne-antiseptic yendawo
I-Adenine, eyaziwa nangokuthi i-6-aminopurine, ingenye yama-nucleobases amane akha i-DNA ne-RNA molecule, enefomula yamakhemikhali ethi C5H5N5.Ihilelekile ekwakhiweni kweziphakathi eziningi ezibalulekile ezifana ne-ATP ne-NADP ezindleleni ze-metabolic emzimbeni.
I-Adenine iyingxenye ye-nucleic acid nama-coenzymes, ehilelekile ekuhlanganiseni kwe-DNA ne-RNA emzimbeni, futhi ibalulekile ekugcinweni kwemisebenzi ye-metabolic yento ephilayo.Indima yayo ukukhuthaza ukwanda kwama-leukocyte uma kwenzeka kuntuleka.
I-synthesis
I-Adenine anabolism ihlanganisa kokubili i-ab initio kanye nezindlela zokulungisa zokwenziwa.I-ab initio synthesis pathway ngokuyinhloko isesibindi futhi isuselwe ku-ribose phosphate, aspartate, glycine, glutamine, namayunithi ekhabhoni eyodwa.Ama-nucleotide e-Purine ahlanganiswa ngokuqhubekayo ngesisekelo sama-molecule e-phosphoribose, hhayi ngokuqala ngokuhlanganisa izisekelo ze-purine zodwa bese ezihlanganisa ne-phosphoribose.Ukuhlanganiswa kokulungisa kwe-purine nucleotides ikakhulukazi ngenxa yokuntuleka kwezinhlelo ze-enzymatic ze-ab initio synthesis ye-purine nucleotides ezicutshini ezithile nasezithweni zomzimba, njengobuchopho nomnkantsha, ukuze kuphela le ndlela ingenziwa, futhi lokhu. indlela yonga amandla nokunye ukusetshenziswa kwe-amino acid ngesikhathi se-ab initio synthesis.
