Umhlinzeki Wokukhiqiza wase-China we-Thymidine Isithombe Esifakiwe

I-thymidine

Incazelo emfushane:

Ulwazi oluvamile
Igama lomkhiqizo: Thymidine
Inombolo ye-CAS: 50-89-5
Inombolo yokungena ye-EINECS: 200-070-4
ifomula yesakhiwo:
Ifomula yemolekyuli:C10H14N2O5
Isisindo se-molecule: 242.23

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ifomula Yesakhiwo

Okomzimba
Ukubukeka:I-Crystalline Powder emhlophe
Umbala:Omhlophe Ukuya Kucishe kube Mhlophe
Ukuminyana: 1.3129 (Isilinganiso esinzima)
Iphuzu Elincibilikayo:186-188 °c(lit.)
Indawo yokubilisa:385.05°c (Isilinganiso esinzima)
I-Refractivity:33 °(c=1, 1mol/l uNaoh)
Ukuzungezisa Okuthile:18.6 º(c=3, H2o)
Isimo Sesitoreji:2-8°c
Isici se-Acidity(pka):pk1:9.79;pk2:12.85 (25°c)
I-spinability:α]20/d +19±1°, C = 1% Ku-H2o
I-Solubility Emanzini:i-soluble
Ukuzinza: uzinzile.Akuhambisani Ne-Ejenti Ye-oxidizing Eqinile

Idatha Yezokuphepha
Isigaba esiyingozi:Akuzona izimpahla eziyingozi
Inombolo yokuthutha impahla eyingozi:
Isigaba sokupakisha:

Isicelo
1.Isetshenziswa njengengxenye yezemithi yokuhlanganiswa kwemithi elwa namagciwane kanye ne-anti-HIV.
2.Njenge-Intermediate ye-Zivdodine

Ukusetshenziswa:
I-Thymidine iyi-deoxyribonucleoside equkethe isisekelo se-thymine.I-Thymidine iyi-nucleoside eyakhiwe ngokuxhumanisa i-thymidine ne-D-ribose ngebhondi ye-β-glycosidic.I-Thymidine isetshenziswa ekulungiseleleni imishanguzo elwa nengculazi (isib. i-zidofuridine, i-stavudine) nasekuhlanganiseni imishanguzo elwa namagciwane.Ingasetshenziswa futhi njengendawo ephakathi kwezemithi futhi ithunyelwe kwamanye amazwe ngokuqondile.
I-Bioactivity:
I-Thymidine(Deoxythymidine,2'-Deoxythymidine,5-Methyldeoxyuridine,DThChemicalbookyd,NSC21548) iyinucleoside yepyrimidine ehlanganisa i-thymine, isisekelo se-pyrimidine esixhunywe ku-sugar deoxyribose.Njengengxenye ye-DNA, i-thymine nucleosides ihambisana ne-adenine ku-DNA double helix.

Okwedlule: I-China 3-Amino-5-methylpyrazole Umhlinzeki Wokukhiqiza

Olandelayo: China L-Prolinamide Manufacture Supplier