Imikhiqizo
I-Orlistat
Ifomula Yesakhiwo
Izakhiwo Zomzimba
Ukubukeka: i-crystalline powder emhlophe
Ukuminyana: 0.976±0.06
Iphoyinti lokuncibilika:<50°C<br /> Indawo yokubilisa: 615.9±30.0°C
Idatha Yezokuphepha
Isigaba esiyingozi: Izimpahla ezijwayelekile
Isicelo
Inhlanganisela ye-micro low calorie diet ifaneleka ekwelapheni isikhathi eside kwabantu abakhuluphele nabakhuluphele ngokweqile, okuhlanganisa nalabo abaye bahlakulela izici eziyingozi ezihlobene nokukhuluphala ngokweqile.Kunomphumela wokulawula isisindo eside (ukulahlekelwa isisindo, ukugcinwa kwesisindo nokuvimbela ukuphindaphinda).Ukuphuza umuthi kunganciphisa izinga lezehlakalo lezinto eziyingozi ezihlobene nokukhuluphala kanye nezinye izifo ezihlobene nokukhuluphala, okuhlanganisa i-hypercholesterolemia nesifo sikashukela sohlobo 2.
I-Orlistat iyi-ejenti engeyona eye-CNS yokwelapha ukukhuluphala.Isebenza kuphela emgudwini wamathumbu, ivimbele i-hydrolysis ye-triacylglycerols ibe ama-fatty acids mahhala kanye ne-monoacylglycerides ngokuvimbela i-lipase emgudwini wesisu, inciphisa ukumuncwa kwamafutha okudla (i-triacylglycerols) nge-mucosa yamathumbu, futhi ikhuthaze ukukhishwa komzimba. .I-Lipase iyi-enzyme edingekayo ukubola kwamafutha emgudwini wesisu.Lo mkhiqizo ungahlangana nezinsalela ze-serine ze-gastric kanye ne-pancreatic lipase ukuze ungasebenzi i-lipase, ukuze ungakwazi ukubolisa amafutha ekudleni abe ama-acids mahhala futhi uvimbele ukusetshenziswa nokumuncwa kwamafutha.
Izinyathelo zokuqapha: 1. Iziguli ezikhuluphele ezinesifo sikashukela sohlobo 2 zilahlekelwa isisindo ngemva kokwelashwa ngalo mkhiqizo, ngokuvamile zihambisana nokulawulwa kwe-glycemic okuthuthukisiwe, futhi zidinga ukulungisa izidakamizwa ze-hypoglycemic ukuze zigweme i-hypoglycemia.
2. Abesifazane abakhulelwe nabancelisayo, izingane ezingaphansi kweminyaka engu-18 ubudala kanye nentsha ayizange ifundelwe ukuphepha nokusebenza kahle, ungasebenzisi.
