... I-Wholesale yaseChina Indole-3-methanol Manufacture Supplier Umkhiqizi Nomphakeli |I-LonGoChem
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Imikhiqizo

Indole-3-methanol

Incazelo emfushane:

I-Indole-3-methanol iyisitshalo sesibili se-metabolite esikhiqizwa emifino e-cruciferous, engakhishwa emifino ye-cruciferous (njenge-broccoli, i-radish ne-cauliflower).I-Indole-3-carbinol iyi-tumor chemopreventive substance.I-Indole-3-carbinol ingavimbela ukwenzeka nokuthuthukiswa kwezinhlobonhlobo zezimila.I-Indole-3-methanol yasetshenziselwa ukufaka i-poly lactic acid co glycolic acid (PLGA) ukutadisha umphumela wayo wokulwa nomdlavuza kumaseli we-adenocarcinoma epithelial cells (MCF7), colon adenocarcinoma epithelial cells (Caco2) kanye namaseli e-prostate epithelial cell (PC3) in vitro.Iphinde isetshenziswe njenge-inducer ye-cytochrome P4501A (CYP1A).


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Incazelo

I-Indole-3-methanol (I3C) yenza i-aromatic hydrocarbon receptor (AHR) isebenze futhi ibangele ukuboshwa komjikelezo weseli ye-G1 kanye ne-apoptosis.Ngakho-ke, i-ejenti engase ibe nomdlavuza.Ngaphezu kwalokho, yenza i-estradiol metabolism ngokuvuselela i-cytochrome P450 enzyme.Ngakho-ke, i-I3C ibhekwa njengomuthi osebenzayo we-chemotherapy wezinhlobo ezahlukene zomdlavuza, kuhlanganise nomdlavuza webele, umdlavuza we-prostate, umdlavuza wekoloni kanye ne-leukemia.I-Indole-3-methanol ingadala kuphela i-apoptosis yamaseli omdlavuza, aphephile futhi angenayo i-cytotoxic kumaseli angewona amathumba.Ngenxa yokusebenza kahle kwayo okuphezulu, izakhiwo ezingezona ezinobuthi nezemvelo zokulwa nesimila, i-indole-3-methanol ingasetshenziswa njengomunye wabantu abazongenela ukhetho lokuvikela umdlavuza kanye nemithi yokwelapha.

Ulwazi Lomkhiqizo

Inombolo yeCas: 700-06-1

Ubumsulwa:≥98%

Ifomula:C9H9NO

Ifomula Wt.:147.17

Igama Lekhemikhali: INDOLE-3-CARBINOL

Igama elifanayo: Indole-3-carbinol, 99.5%;Indole-3-carbinol98%;(1H-Indol-3-yl)-methano;I-Indol-3-yl-methanol;3-INDOLAMETHChemicalbookANOL;INDOLE-3-CARBINOL: 3-INDOLEMETHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)

Ukuncibilika: 96-99 °C

Indawo yokubilisa:267.28°C

Ukubukeka: Okumhlophe-kumhlophe ukuya kophuzi-owolintshi okuyimpushana ecwebezelayo noma ama-flakes

Ukuthumela kanye Nesitoreji

Ukuzinza kwesitoreji Izinga lokushisa elinconywayo lesitoreji ngu-2 - 8 °C.


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